Asian Journal of Transfusion Science
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Year : 2019  |  Volume : 13  |  Issue : 2  |  Page : 140-141

An unusual report of anti-N antibody presenting as ABO discrepancy in an old female patient in Palestine

1 Department of Medical Technology, Faculty of Allied Health Sciences, Arab American University, Jenin, Palestine
2 Department of Biology and Biochemistry, Faculty of Science, Birzeit University, Birzeit, Palestine

Correspondence Address:
Fekri H Samarah
Department of Medical Technology, Faculty of Allied Health Sciences, Arab American University, Jeni, Palestine

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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ajts.AJTS_28_18

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The MNS is a highly complex immune blood group system which is almost equal to Rh in size and complexity. Anti-N antibody is naturally occurring in general, cold reactive IgM or IgG saline agglutinin and relatively rare when compared with anti-M. The immune type anti-N is seldom encountered. Anti-N antibody is not clinically significant unless it reacts at 37°C. Clinically significant anti-N antibody is reactive at 37°C or in the anti-human globulin phase, which may cause delayed hemolytic transfusion reactions or hemolytic disease of newborn. Here, we report a rare case presented as blood group discrepancy of a naturally occurring anti-N that reacts at 37°C.

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2006 - Asian Journal of Transfusion Science | Published by Wolters Kluwer - Medknow
Online since 10th November, 2006