Asian Journal of Transfusion Science
Home About Journal Editorial Board Search Current Issue Ahead of print Back Issues Instructions Subscribe Login  Users: 399 Print this page  Email this page Small font sizeDefault font sizeIncrease font size 
Year : 2021  |  Volume : 15  |  Issue : 2  |  Page : 183-188

Risk factors associated with human immunodeficiency virus infection in blood donors in Iran: A case–control study

1 Blood Transfusion Research Center, High Institute for Research and Education on Transfusion Medicine; Department of International Affairs, Iranian Blood Transfusion Organization, Tehran, Iran
2 Department of International Affairs, Iranian Blood Transfusion Organization, Tehran, Iran; Department of Global Health Policy, Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, UK
3 Department of Research and Education, Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine; Department of Epidemiology, Iran University of Medical Science, Tehran, Iran
4 Department of Blood Donor, Tehran Blood Transfusion Center, Tehran, Iran

Correspondence Address:
Mrs. Nasim Sadat Hosseini Divkolaye
Iranian Blood Transfusion Organization BLDG, Hemmat EXPY, Adjacent to Milad Tower, Tehran

Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ajts.AJTS_47_18

Rights and Permissions

BACKGROUND: Despite setting the stringent criteria for the selection of safe donors, some human immunodeficiency virus (HIV)-positive volunteers manage to give blood. Considering the window period of screening tests, this could endanger the safety of blood supply. MATERIALS AND METHODS: A frequency match case–control study was conducted on HIV-positive and negative blood donors in Iran from 2007 to 2008. Overall, 61 HIV-positive and 224 HIV-negative blood donors were selected as cases and controls, respectively. Two groups were matched for confounding factors. An identical questionnaire was used to assess risk factors. Univariate regression analysis for calculating crude odds ratio (OR) and 95% confidence interval (CI) was used for detecting eligibility of risk factors to enter the final model. The exposures with P < 0.1 were entered in the logistic regression model. Adjusted ORs with P < 0.05 and 95% CIs were reported for statistically significant variables. RESULTS: Significant effects were detected for the following variables: education, job, tattoo, intravenous (IV) drug abuse, imprisonment, and risky sexual behavior. However, based on multiple analyses, education, IV drug abuse, imprisonment, and risky sexual behavior remain significant. CONCLUSION: The majority of our findings are in parallel with the other studies performed in other countries. To increase blood safety, special attention should be paid to illiterate, first-time blood donors who are in the 25–40 age range. In addition, having the history of IV drug abuse, imprisonment and risky sexual behaviors put the blood donors more at risk of infecting HIV.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded177    
    Comments [Add]    

Recommend this journal


Association Contact us | Sitemap | Advertise | What's New | Copyright and Disclaimer | Privacy Notice

2006 - Asian Journal of Transfusion Science | Published by Wolters Kluwer - Medknow
Online since 10th November, 2006