Asian Journal of Transfusion Science
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CASE REPORT
Year : 2021  |  Volume : 15  |  Issue : 2  |  Page : 229-232

Case report and strategies to mitigate passive hemolysis with platelet transfusions in children


1 Division of Transfusion Medicine, Malabar Cancer Centre, Thalassery, Kerala, India
2 Division of Pediatric Oncology, Malabar Cancer Centre, Thalassery, Kerala, India

Correspondence Address:
Mohandoss Murugesan
Division of Transfusion Medicine, Malabar Cancer Centre, Thalassery, Kerala
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ajts.ajts_25_21

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Mismatched platelet concentrate transfusion due to inadequately maintained inventories is relatively common and in most instances do not cause any untoward event in adults. The cases of passive hemolysis following a mismatched apheresis platelet transfusion are common but are relatively rare with platelet concentrates. We report here a case of a nine year old boy who received three units of mismatched platelet concentrates(PC) followed by acute hemolysis. On further investigation, one of the donors of the PC, who was typed as O positive, found to have high anti-A and anti-B titres of 1:128. This highlights the importance of matched platelet transfusions or modifying the product in pediatric setting, who are susceptible for passive hemolysis.


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2006 - Asian Journal of Transfusion Science | Published by Wolters Kluwer - Medknow
Online since 10th November, 2006