| CASE REPORT |
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| Year : 2023 | Volume
: 17
| Issue : 1 | Page : 117-120 |
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Effectiveness of therapeutic plasma exchange in case of rare neurological disorder Isaacs syndrome
Parmatma Prasad Tripathi1, Sangeeta Kumari1, Nandita Prabhat2, Divjot Singh Lamba1, Rekha Hans1, Manoj Kumar Goyal2, Vivek Lal2, Ratti Ram Sharma1
1 Department of Transfusion Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India
2 Department of Neurological Science, Post Graduate Institute of Medical Education and Research, Chandigarh, India
Correspondence Address:
Ratti Ram Sharma
Department of Transfusion Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh Sector-12, Chandigarh
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/ajts.ajts_88_21
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Isaacs syndrome is a disease characterized by nerve hyperexcitability and pseudomyotonia and treated with immunomodulatory and symptomatic therapy approaches. Here, we report a case of anti-(leucine-rich glioma-inactivated 1) antibody-positive patient diagnosed as Isaacs syndrome and accomplished a nearly complete response to only four sessions of therapeutic plasma exchange (TPE). Our experience suggests that TPE along with other immunomodulatory agents may be beneficial and well-tolerated approach in patient with Isaacs syndrome.
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