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Outcome of pregnancy in sickle cell anemia patients with COVID-19 infection
Vaidyanathan Gowri1, Tamima Al Dughaishi1, Deepti Geetha1, Marwa Al Riyami1, Radhiya Alburaidi2, Salam Al Kindi1
1 Department of Obstetrics and Gynecology, Sultan Qaboos University, Muscat, Oman
2 Department of Inetrnal Medicine, Nizwa Hospital, Oman
Correspondence Address:
Vaidyanathan Gowri,
PO Box 35, college of Medicine and health Sciences, Sultan Qaboos University, Muscat, Postal code 123
Oman
 Source of Support: None, Conflict of Interest: None DOI: 10.4103/ajts.ajts_164_21
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Sickle cell anemia (SCA) is a multisystem disease, associated with increased risk for infection and thromboembolic disease, and pregnancy is a stressor for patients with SCA. In general, coronavirus disease 2019 (COVID-19) infection in SCA is associated with a favorable outcome. Literature of pregnancy in SCA with COVID is scarce. We report a case series study of pregnant women with SCA, who are confirmed positive for COVID-19 from May 2020 to March 2021. These patients showed generally mild-to-moderate disease and presented predominantly with fever and painful crisis. They showed a significant drop in Hb from baseline, and they received low-molecular-weight heparin prophylaxis (LMWH) and blood transfusion. The outcome of pregnancy is satisfactory, although the mean birth weight was significantly lower than that reported from the same SCA population.
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