Asian Journal of Transfusion Science
Home About Journal Editorial Board Search Current Issue Ahead of print Back Issues Instructions Subscribe Login  Users: 6571 Print this page  Email this page Small font sizeDefault font sizeIncrease font size 
 
CASE REPORT
Ahead of Print

Platelet count in impedance-based hematology analyzer: Beware of trap!


1 Department of Pathology, JSS Medical College, Mysore, Karnataka, India
2 Department of Hematology, Anand Diagnostic Laboratory, Bengaluru, Karnataka, India

Correspondence Address:
Vani Krishnamurthy,
#70, Prakruthi, BEML 2nd Stage, Rajarajeshwari Nagara, Mysuru - 570 022, Karnataka
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ajts.ajts_65_21

Among the blood counts, platelet count is most often reported with inconsistency. Many of the analyzers work on electrical impedance principle for red blood cell (RBC) and platelet counting. However, with this technology, factors such as fragmented RBCs, microcytes, cytoplasmic fragments of leukemic cells, lipid particles, fungal yeast forms, and bacteria are known to interfere with platelet count and give spuriously elevated platelet counts. A 72-year-old male was admitted for the treatment of dengue infection who had serial platelet count monitoring. He had an initial platelet count of 48,000/cumm which suddenly improved to 2.6 lakhs within 6 h without any platelet transfusion. Peripheral smear however did not correlate with the machine-derived count. Repeat test after 6 h yielded a result of 56,000/cumm which correlated well with the peripheral smear. This falsely elevated count was due to the presence of lipid particles as the sample was drawn in the postprandial state.


Print this article
Search
 Back
 
  Search Pubmed for
 
    -  Krishnamurthy V
    -  Shivamurthy A
    -  Kumar PV
 Citation Manager
 Article Access Statistics
 Reader Comments
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed236    
    PDF Downloaded25    

Recommend this journal

Association Contact us | Sitemap | Advertise | What's New | Copyright and Disclaimer | Privacy Notice


2006 - Asian Journal of Transfusion Science | Published by Wolters Kluwer - Medknow
Online since 10th November, 2006