Asian Journal of Transfusion Science
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Mean peroperative blood transfusion requirement in living donor liver transplant recipients

 Hematology Department and Blood Bank, Blood Transfusion Services, Shifa International Hospital; Department of Hepatobiliary and Liver Transplant, Shifa International Hospital, Islamabad, Pakistan

Correspondence Address:
Shabana Shumail,
Hematology Department and Blood Bank, Shifa International Hospital Ltd., Sector H8/4, Islamabad
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ajts.AJTS_14_20

CONTEXT: Excessive bleeding in living donor liver transplantation is a foremost confrontation for transplant surgeons globally. Despite improvement in technical aspects, patient care, graft allocation, and use of blood-sparing policies, excessive blood loss still occurs. Blood transfusion services play a crucial role in providing both quantitative and qualitative support. AIMS: This study is aimed at estimating the average transfusion requirement in terms of packed red cells (PRCs), fresh-frozen plasma (FFP), platelet concentrates, and cryoprecipitates in liver transplant recipients and analyzing predictors in our local circumstances. This would provide a guideline for anticipating the required blood component for centers intending to undertake this challenging task. SETTINGS AND DESIGN: Descriptive cross-sectional study was conducted at Blood Transfusion Services and Department of Hepatobiliary and Liver Transplant, Shifa International Hospital, Islamabad. SUBJECTS AND METHODS: Intraoperative utilization of blood components in 148 living donor liver transplant recipients was analysed using SPSS (IBM Statistical product and service solution version 20.0 (SPSS, Chicago, IL, USA). RESULTS: The mean perioperative blood loss was 2845 ± 265 ml requiring a mean transfusion of 3. 43 ± 2.8 PRCs, 3.54 ± 5.0 units of FFP, 7.94 ± 7.6 units platelet, and 5.56 ± 7.4 units of cryoprecipitates. CONCLUSIONS: Anticipation of mean blood loss and transfusion requirement along with close collaboration between the transplant team and blood transfusion services can help better streamlining the resources to provide adequate and timely services.

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2006 - Asian Journal of Transfusion Science | Published by Wolters Kluwer - Medknow
Online since 10th November, 2006