Asian Journal of Transfusion Science
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CASE REPORT
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Effectiveness of therapeutic plasma exchange in case of rare neurological disorder Isaacs syndrome


1 Department of Transfusion Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India
2 Department of Neurological Science, Post Graduate Institute of Medical Education and Research, Chandigarh, India

Correspondence Address:
Ratti Ram Sharma,
Department of Transfusion Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh Sector-12, Chandigarh
India
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ajts.ajts_88_21

Isaacs syndrome is a disease characterized by nerve hyperexcitability and pseudomyotonia and treated with immunomodulatory and symptomatic therapy approaches. Here, we report a case of anti-(leucine-rich glioma-inactivated 1) antibody-positive patient diagnosed as Isaacs syndrome and accomplished a nearly complete response to only four sessions of therapeutic plasma exchange (TPE). Our experience suggests that TPE along with other immunomodulatory agents may be beneficial and well-tolerated approach in patient with Isaacs syndrome.


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2006 - Asian Journal of Transfusion Science | Published by Wolters Kluwer - Medknow
Online since 10th November, 2006