Asian Journal of Transfusion Science

: 2009  |  Volume : 3  |  Issue : 2  |  Page : 70--72

Hyperbilirubinemia in normal healthy donors

Veena Arora, RK Kulkarni, Susan Cherian, Raji Pillai, M Shivali 
 Blood Bank, Pathology Department, B.A.R.C Hospital, Mumbai - 400 094, India

Correspondence Address:
Veena Arora
Pathology Unit, BARC Hospital, Anushaktinagar, Mumbai - 400 094

The present study was carried out in B.A.R.C. Hospital Blood Bank over a span of five years, and includes 2734 donors. All the bags were screened for HIV, HBsAg, HCV and VDRL and the plasma in the pilot tubes of the blood bags was observed to detect any abnormality in color. In 27 cases plasma was found to be icteric and liver function tests were carried out on these samples. Two donors showed higher SGPT level, and were excluded. No significant increases in liver enzymes were recorded in the others. Causes of icteric plasma in these apparently healthy donors are discussed. Differential diagnosis includes Gilbert«SQ»s disease, hemolytic anemia, drug-induced anemia and other hepatic causes of hyperbilirubinemia, of which Gilbert«SQ»s disease is most probable cause with a prevalence of 0.91% in our population. As there are no studies to document the safety of the recipients receiving such abnormal colored plasma as well as to document the hazards in its transfusion, the question arises whether to transfuse such units or not. This study highlights this dilemma. A reassessment of existing policies and regulations is merited.

How to cite this article:
Arora V, Kulkarni R K, Cherian S, Pillai R, Shivali M. Hyperbilirubinemia in normal healthy donors.Asian J Transfus Sci 2009;3:70-72

How to cite this URL:
Arora V, Kulkarni R K, Cherian S, Pillai R, Shivali M. Hyperbilirubinemia in normal healthy donors. Asian J Transfus Sci [serial online] 2009 [cited 2022 Sep 26 ];3:70-72
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